Adsorption Isotherms of Tryptophan Enantiomer on D-Tryptophan Molecular Imprinted Polymer

Y. Jin1,2, C.C. Liu1,2, X.H. Sun1,2, K.J. Lee2,3, Y.A. Jung2,4 and K.H. Row2,*

1College of Food Science and Technology, Shanghai Ocean University, Shanghai 201-306, P.R. China

2Department of Chemical Engineering, Inha University, Incheon 402-751, South Korea

3College of Pharmacy, University of Hawaii, 924 Stainback Highway, Hio, HI 96720, USA

4Fine Chemical Analysis & Research Team, Korea Machinery-Meter and Petrochemical Testing & Research Institute, Seoul 135-120, South Korea

*Corresponding author: Fax: +82 32 8720959; Tel: +82 32 8607470; E-mail: rowkho@inha.ac.kr

Abstract

A molecular imprinted polymer using D-tryptophan as a template and methacrylic acid and acrylamide as a functional co-monomer was prepared. Water and methanol were used as the hydrophilic porogen with ethylene glycol dimethacrylate as the crosslinker and 2,2'- azobis(isobutyronitrile) as the initiator. Comparison of D and L form of tryptophan adsorption isotherm on molecular imprinted polymer was made by the static method. The experimental parameters in the equilibrium isotherms were estimated by linear and nonlinear regression analyses. The linear equation for concentration and sorbents to adsorption concentrations was then expressed and the adsorption equilibrium data were correlated into Langmuir, Freundlich, quadratic, Allometric, Langmuir and Freundilich extension isotherm models. The calculated data is well fitted with the experimented data. The D-tryptophan imprinted polymer showed extraordinarily higher adsorption ability for D-tryptophan than the L-tryptophan compounds that were also assessed. Furthermore, the competitive Langmuir isotherms were applied to the mixture compounds of D and L form tryptophan.

Keywords

Adsorption isotherm, Molecular imprinted polymer, Tryptophan, Enantiomer, Hydrophilic porogen.

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  • Asian J. Chem. /
  •  2012 /
  •  24(6) /
  •  pp 2461-2466