Effect of Three Pesticides on Chlorogenic Acid Concentration of Lonicera japonica Thunb

Xiaobo Wu, Jian Xue*, Linlin Zhang, Nan Sun and Dongjing Liu

Department of Natural Medicine Chemistry Research Center, Institute of Medicinal Plant Development, Chinese Academy of Medical Science and Peking Union Medical College, Beijing 100193, P.R. China

*Corresponding author: Fax: +86 1057833097; Tel: +86 1062895076; E-mail: xuejian5076@yahoo.com.cn


Lonicera japonica Thunb flowers are widely used in Chinese medicine as an antipyretic. However, production of this medicinal plant is commonly affected by diseases such as powdery mildew in Feng Qiu area of China. A field study was conducted in 2005 and 2006 to investigate the influence of two insecticides (imidacloprid and acetamiprid) and one fungicide (triadimefon) on concentration of chlorogenic acid in flowers of Lonicera japonic. The Lonicera japonic was sprayed with imidacloprid and triadimefon at 1x and 3x field recommend rate and sprayed with acetamiprid at 1x and 5x field recommend rate at flowering stage. Results showed that the 1x and 5x field recommended rate of acetamiprid increased the concentration of chlorogenic acid (p < 0.05) in 2005 and 2006, while imidacloprid and triadimefon in 2005 had no significant effects (p > 0.05) on chlorogenic acid concentration. But 1x and 3x field recommended rate of triadimefon had significant effects (p < 0.01) on the chlorogenic acid concentration and decreased the concentration in 2006.


Acetamiprid, Chlorogenic acid, Imidacloprid, Lonicera japonica, Triadimefon.

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  • Asian J. Chem. /
  •  2012 /
  •  24(9) /
  •  pp 3829-3832