Asian Journal of Chemistry ::

Synthesis, Spectroscopic and Biological Activities of Aromatic Schiff Base
Manawwer Alam^1,*, Naser M. Alandis², Mohammed Rafi Shaik², Shahanavaj Khan³ and Suliman Y. Alomar⁴
¹Research Center-College of Science, King Saud University, P.O. Box. 2455, Riyadh 11451, Kingdom of Saudi Arabia ²Department of Chemistry, College of Science, King Saud University, P.O. Box. 2455, Riyadh 11451, Kingdom of Saudi Arabia ³Department of Pharmaceutics, College of Pharmacy, King Saud University, P.O. Box. 2457, Riyadh 11451, Kingdom of Saudi Arabia ⁴Department of Zoology, College of Science, King Saud University, P.O. Box, 2455, Riyadh 11451, Kingdom of Saudi Arabia *Corresponding author: Tel: +966 554738803; E-mail: malamiitd@gmail.com
Abstract In this paper the preparation of 5-[(2-aminophenyl)imino]-3,3-dimethylcyclohexanone and 5-[(4-aminophenyl)imino]-3,3-dimethyl cyclohexanone in the ethanolic medium. The structures of these compounds were characterized by elemental analysis, FT-IR, ¹H-NMR and ¹³C-NMR. The antibacterial and antifungal activity of these compounds has been investigated by agar disc diffusion method using Gram-negative and Gram-positive bacterial strain and four kinds of fungi.
Keywords Schiff base, Dimedone, o-Phenylenediamine, p-Phenylenediamine.
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Asian J. Chem. / 2014 / 26(21) / pp 7377-7380 https://doi.org/10.14233/ajchem.2014.17036

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