A Novel Method for Synthesis of 1,4-Dihydropyridines Using Robust Laterite Catalyst under Ultrasonic Irradiation

S.S. Chine1 and C.S. Patil2,*

1Department of Engineering Sciences, SRES' Sanjivani College of Engineering, Kopargaon-423601, India

2Department of Chemistry, Deogiri College, Aurangabad-431005, India

*Corresponding author: E-mail: chabu251962@yahoo.co.in


An efficient method for the synthesis of 1,4-dihydropyridine derivatives from various aryl or heteroaryl aldehydes, β-ketoester and ammonium acetate in presence of laterite catalyst in ethanol under ultrasonication is reported. Catalyst study done with wet chemical analysis, FT-IR, XRD, SEM and EDS techniques. The catalyst can be recovered and reused without noticeable loss of activity even after five cycles.


Laterite, Wet chemical analysis, Ultrasonication, Heterogeneous catalysis

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