Novel Synthesis of Hexahydrochromeno[4,3-b]pyrrolo[2,1-a]isoquinolines via C-H Functionalization

H.E. Dinesha and K. Mantelingu*

Department of Chemistry, University of Mysore, Mysore-560 002, India

*Corresponding author: E-mail: kmlingu@gmail.com

Abstract

In present work, an efficient and direct method for the synthesis of hexahydrochromeno[4,3-b]pyrrolo[2,1-a]isoquinolines is reported. This method involves ®T3P mediated oxidation of alcohols to aldehydes followed by [3+2] cycloaddition to afford hexahydrochromeno[4,3-b]pyrrolo[2,1-a]isoquinolines with good yields.

Keywords

C-H Functionalization, ®T3P, [3+2] Cycloaddition, Chromene, Isoquinolines

   View Article PDF File Under a Creative Commons License