Microwave Assisted One Pot Synthesis of 3,4-Dihydropyrano[c]chromene Derivatives using [Emim]OH Ionic Liquid as Novel Catalyst

D.S. Bhagat1,*, S.G. Pande1, M.V. Katariya2, R.P. Pawar2 and P.S. Kendrekar3

1Department of Forensic Chemistry, Government Institute of Forensic Science, Aurangabad-431001, India

2Department of Chemistry, Deogiri College, Station Road, Aurangabad-431005, India

3Department of Health Sciences, Central University of Technology, Bloemfontein 9300, Free State, South Africa

*Corresponding author: Tel/Fax: +91 240 2400219; E-mail: dsbhagat999@gmail.com

Abstract

One-pot efficient protocol to the synthesis of 2-amino-5-oxo-4,5-dihydropyrano(3,2-c)chromene-3-carbonitrile derivatives via condensation of various aryl aldehydes, dicyanomethane and 4-hydroxycoumarin in presence of Emim hydroxide as an excellent homogeneous liquid catalyst. The key advantages of this methodology are mild reaction conditions, novel catalyst, short reaction time, eco-friendly, easy work-up procedure and high yield of isolation of derivatives.

Keywords

Microwave assisted, [Emim]OH, Homogeneous catalyst, Green approach, 3,4-Dihydropyrano[c]chromene.

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