Synthesis and Characterization of Chemically Cross-Linked CMC/Acrylamide Hydrogels

Shivakumara Lachakkal Rudrappa1, Sudhir Ramaswamy Iliger2 and Demappa Thippaiah1,*

1Department of Post-Graduate Studies and Research in Polymer Science, University of Mysore, Sir M. Visvesvaraya Post Graduate Centre, Tubinakere, Mandya-571402, India

2Department of Pharmaceutics, SET’s College of Pharmacy, S.R. Nagar, Dharwad-580002, India

*Corresponding author: E-mail: demappa@uni-mysore.ac.in

Abstract

Carboxymethyl cellulose/poly(acrylamide) (CMC/Amm) hydrogels were synthesized by the chemical cross-linking method. Ammonium persulfate used as an initiator, while aluminium sulfate used as a cross-linking agent. The structure and morphology of the hydrogels were characterized by FTIR and scanning electron microscopy (SEM) analysis. The swelling behaviour of the hydrogels can be studied by using acids (CH3COOH, HCl and HClO4) and also in the pH of the buffer solutions at different temperature (room temperature, 30 and 37 ºC) was studied. Swelling of hydrogels increased with an increase in the concentration of aluminum sulfate up to 20 %, above 20 % it has found to be decreased. The effect of four series of cationic different concentrated salt solutions on the swelling had found to be the following order K+ > Na+ > Ca2+ > Mg2+.

Keywords

Acrylamide, Carboxy methyl cellulose, Cross-linking agent, Hydrogels, Initiator.

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