Solubility Data of Glycine in Water and Justification of Literature Results: A Review

Arup Datta1, Aslam Hossain2, Partha Sarathi Guin1 and Sanjay Roy1,*

1Department of Chemistry, Shibpur Dinobundhoo Institution (College), Howrah-711102, India

2Department of Physical and Inorganic Chemistry, Institute of Natural Sciences and Mathematics, Ural Federal University, Lenin Av. 51, Ekaterinburg 620000, Russia

*Corresponding author: E-mail:


Glycine has been studied more than other amino acids. However, there are still insufficient reviews in the field related to glycine solubility data which is why in the present review authors have collected many solubility data of glycine in pure water and in the presence of inorganic and organic electrolytes from previous articles. In the current review, authors have considered 145 results reported in 45 published articles. On the origin of the reported results on the solubility, a very easy linear model was applied to get a better fit for accurate solubility measurement. By analyzing the results authors expressed the solubility of glycine as a linear function of temperature with a change of solubility of 0.0866 mol kg-1/K. The results were applied for the statistical analysis to estimate an accurate value of solubility which was found as 3.318 mol kg-1 at 298.15 K.


Solubility, Glycine, Linear model, Standard deviation.

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